Levamisole – worming medication.
Acting on gangliopodobnye formation nematodes causes Dekaris depolyariziruyuschuyu neuromuscular paralyzing muscle membrane helminths, succinate dehydrogenase blocks, inhibits fumaratdegidrogenazu, bioenergetic processes for breaking helminths.
Thus, paralyzed nematodes are removed from the body normal peristalsis of the intestine within 24 hours after ingestion.
Gedeon Richter, Hungary
1 tablet contains:
The active ingredient is:
levamisole hydrochloride – 177 mg, which corresponds to the content of levamisole – 150 mg.
- The infestation by helminths Ascaris lumbrocoides, Necator and Americanus Ancylostoma duodenale.
- Agranulocytosis caused by medicaments (history).
- Children under 3 years old.
- The period of breastfeeding.
- 150 mg tablets are not indicated for children.
Precautions: patients with renal and / or hepatic insufficiency, inhibition of bone marrow hematopoiesis.
Headache, insomnia, dizziness, palpitations, seizures, dyspepsia (nausea, vomiting, abdominal pain, diarrhea).
There are about development posts side effects of the central nervous system (encephalopathy) within 2-5 weeks after taking the drug, as well as allergic reactions (skin rash), convulsions.
In most patients, these effects were reversible, and early application of glucocorticosteroid therapy improves the prognosis.
The relationship of these symptoms with taking dekaris not entirely convincing. At high doses or prolonged therapy leukopenia can occur, agranulocytosis, tremor.
How to accept, acceptance rate and dosage
1 tablet 150 mg.
Store at a temperature of 15-30 ° C.
Keep out of the reach of children.
At the same time taking the drug with alcohol disulfiramopodobnye observed phenomena.
caution is required when applying dekaris with drugs affecting hematopoiesis.
When simultaneous administration of the drug with kumarinopodobnymi anticoagulants prothrombin time may increase, so it is necessary to adjust the dose oral anticoagulant. Dekaris increases levels of phenytoin in blood, so while their application must monitor the level of phenytoin in blood.
Dekaris can not simultaneously use with lipophilic drugs, such as carbon tetrachloride, tetrachlorethylene, henopodiya oil, ether or chloroform, since its toxicity may increase.
During and after taking the drug for 24 hours, you can not drink alcohol. There is insufficient data that levamisole, used as anthelmintics, depresses the nervous system.
Effect on ability to drive and other mechanisms
Due to the fact that while taking the drug may be a transient, mild dizziness, caution should be exercised when driving or operating machinery during the course of treatment.
Pregnancy and lactation
Use of the drug during pregnancy is possible only when the intended benefits to the mother outweighs the potential risk to the fetus.
If necessary, use during lactation should decide the issue of termination of breastfeeding.
Symptoms when administered high doses of levamisole (over 600 mg) were described by the following signs of intoxication: nausea, vomiting, drowsiness, seizures, diarrhea, headache, dizziness and confusion.
Treatment: the accidental overdose and if, after administration of the drug was not long, gastric lavage performed. Requires monitoring of vital functions and symptomatic therapy. If there are signs of anticholinesterase action can atropine.