Ferrovir 1,5% 5 ml 5 pcs

Pharmacodynamic

Ferrovir activates antiviral, antifungal and antimicrobial immunity. It exhibits an antiviral effect towards RNA- and DNA-containing viruses.

Course use (within 14 days) in the treatment of AIDS / HIV infection enhances CD4 + lymphocytes in the blood. This increase lasts for 1-1.5 months after the end of treatment. Simultaneously decreasing the viral load in the body, resulting in lowering the concentration of HIV RNA compared to the baseline.

When recurrent herpes virus infection is reduced relapse duration, and long-term remission occurs after a 10-day course of treatment.

In the complex treatment of patients with chronic hepatitis C treatment improves portability (decrease dizziness, nausea, etc.), reduction of viral replicative activity of HCV all genotypes and transfer process in the latent phase with restoration of liver cells and inhibition of viral replication. In the presence of active viruses and the primary opportunistic diseases. There is evidence of positive Ferrovir therapy of diseases caused by the human papilloma virus and Epstein-Barr virus.

pharmacokinetics

In intramuscular a rapidly absorbed and distributed in organs and tissues via endolymphatic transportation way; It has high affinity for organs hematopoietic system; He has been actively involved in cellular metabolism, embedding into cell structures. During the course of daily application has the property cumulated in organs and tissues. The time to reach Cmax is 0.5 hours (then begins lowering blood concentration of the drug associated with its distribution in organs and tissues). T1 / 2 – 36 hours.

Repeated administration (every 24 hours for 4 days) was observed drug accumulation in the spleen, lymph nodes, and bone marrow (after the fifth administration of the drug concentration in all organs and tissues is not increased, there is a gradual decrease). Excreted from the body as metabolites, mainly in the urine and the faeces partly. The average retention time of the drug in tissues and organs – 72 hours.

Active substance:
Desoxyribonucleate sodium with ferrum complex

Manufacturer

Tehnomedservis, Russia

Composition

1 ml solution for intramuscular administration contains:

active ingredients:

sodium deoxyribonucleat 15 mg of ferric chloride and ferric 0,048 mg;

excipient:

water for injections.

Indications

• herpesvirus infections of various localization caused by the herpes simplex virus 1 and type 2, including generalized in immunonekompetentnyh persons;
• chronic recurrent genital herpes;
• papillomavirus infection, the treatment of pathological conditions (warts, warts, dysplasia) caused by human papillomavirus;
• Cervical Dysplasia etiopathogenetic therapy (CIN I, CIN II), associated with the virus HPV human papillomavirus;
• cytomegalovirus;
• Hepatitis C;
• encephalitis;
• In the combination therapy of HIV-infected patients and AIDS patients, HIV-infected patients with hepatitis C, HIV-infected patients with recurrent herpes infection.

Contraindications

• idiosyncrasy;
• pregnancy;
• lactation;
• children’s age.

Side effects

Perhaps transient increase in body temperature (to 38 ° C), redness and tenderness at the injection site.

How to accept, acceptance rate and dosage

Ferrovir administered intramuscularly.

When herpes infection – 5 ml (15 mg / ml) solution, 2 times a day, for 10 days.

In chronic recurrent genital herpes, cytomegalovirus infection – 5 ml (15 mg / ml), 2 times a day for 10-15 days.

In the treatment of HIV infection or AIDS, adult – 5 ml (15 mg / ml) for intramuscular administration solution (75 mg on dry basis), 2 times a day (150 mg) for 14 days. If necessary, after 1-1.5 months reappointed therapy.

In the treatment of hepatitis C Ferrovir administered intramuscularly, 2 times a day by 5 ml (15 mg / ml) for 14 days. In the next 14 days the drug is administered at the same daily dose every other day.

When the tick-borne encephalitis – 5 ml (15 mg / ml), 2 times a day for 5 – 10 days.

When papillomavirus infection – 5 ml (15 mg / ml) one time per day, with an interval of 72 hours for 10 days.

With recurrent genital warts either as a monotherapy or in combination with surgical treatment drug prescribed by 5 ml (15 mg / ml) solution for intramuscular injection 2 times a day, for 10 days.

In cervical dysplasia associated with human papillomavirus, the drug prescribed to 5 ml (15 mg / ml) solution of 1 times a day for 10 days.

When using intramuscular solution 2ml produce recalculated until the course dose 750 – 2100 mg.

Storage conditions

In the dark place at a temperature of 4-20 ° C

Active substance

Desoxyribonucleate sodium with ferrum complex

Interaction

Moderately potentiates the effect of anticoagulants.

The combination therapy decreases the toxicity and adverse effects of the drugs (antibacterial, antiviral, antifungal and cytostatic) in connection with cytoprotective properties and optimization of metabolic processes in hepatocytes.

Special conditions

To reduce morbidity Ferrovir intramuscularly administered slowly, over 1-2 minutes.

The solution for injection should be fully used immediately after opening the bottle, do not store open bottles.

Intravenous administration of the drug is not permitted!