Galavit rectal suppositories 100 mg, 10 pcs.

Immunomodulating drug with anti-inflammatory effect.

The mechanism of action is associated with the ability to influence the functional and metabolic activity of macrophages. In inflammatory diseases, it reversibly (for 6-8 hours) inhibits the excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, reactive oxygen species by hyperactive macrophages, which determine the degree of inflammatory reactions, their cyclicality, as well as the severity of intoxication.

Normalization of the functional state of macrophages leads to the restoration of antigen-presenting and regulatory functions of macrophages, and a decrease in the level of autoaggression.

The drug stimulates the bactericidal activity of neutrophilic granulocytes, enhancing phagocytosis and increasing the body’s non-specific resistance to infectious diseases.

The main pharmacological effects are observed within 72 hours.

Active substance:
Aminodihydrophthalasindione sodium

Manufacturer

Salvim, Russia

Composition

1 rectal suppository contains:

Active substance:

aminodihydrophthalazinedione sodium – 100 mg.

Excipients:

 Witepsol W-35 (fatty acid glycerides),

Vitepsol H-15 (glycerides of fatty acids).

Indications

As an immunomodulator and anti-inflammatory agent in complex therapy in adults:

• Infectious intestinal diseases accompanied by intoxication and / or diarrhea.
• Peptic ulcer of the stomach and duodenum.
• Viral hepatitis.
• Chronic recurrent diseases caused by the herpes virus.
• Human papillomavirus (HPV) diseases.
• Infectious and inflammatory diseases of the urogenital tract (urethritis of chlamydial and trichomonas etiology, chlamydial prostatitis, acute and chronic salpingoophoritis, chronic endometritis).
• Purulent-inflammatory diseases of the pelvic organs (PID).
• Postoperative rehabilitation of patients with uterine myoma.
• Complications of the postoperative period in patients of reproductive age.
• Postoperative purulent-septic complications and their prevention (including in cancer patients).
• Chronic recurrent furunculosis, erysipelas.
• Asthenic conditions, neurotic and somatoform disorders, decreased physical performance (including in athletes).
• Mental, behavioral and post-withdrawal disorders in alcohol and drug addiction.
• Inflammatory diseases of the mucous membrane of the mouth and throat, periodontal disease.

Contraindications

• Pregnancy.
• Lactation.
• Individual intolerance.

Side effects

Rarely: allergic reactions.

Interaction

There were no cases of incompatibility of Galavit with other drugs.

How to take, course of administration and dosage

The dosage regimen and duration of therapy are set individually depending on the nature, severity and duration of the disease.

The drug should be used rectally. The suppository is freed from contour packaging and then introduced into the rectum. The intestines are recommended to be freed first.

In acute intestinal infections accompanied by diarrhea: the initial dose is 2 supp. once. Then – 1 supper. 2 times / day until relief of symptoms of intoxication. Possible subsequent continuation of the course of 1 supp. with an interval of 72 hours. The course is 20-25 supp.

With peptic ulcer of the stomach and duodenum in the acute period: the drug is prescribed for 2 supp. 1 time / day for 2 days, then – 1 supp. with an interval of 72 hours. The course is 15-25 supp. In the chronic period, the drug is prescribed for 5 days, 1 supp. 1 time / day, then – 1 supp. after 72 hours. The course is 20 supp.

With viral hepatitis: the initial dose is 2 supp. 1 time / day, then 1 supp. 2 times / day until relief of symptoms of intoxication and inflammation. Possible subsequent continuation of the course of 1 supp. with an interval of 72 hours. The course is 20-25 supp.

In case of chronic recurrent herpetic infection: appoint 1 supp. within 5 days, then – 1 supp. every other day for 15 days.

For diseases caused by HPV: the drug is prescribed for 5 days for 1 supp. 1 time / day, then – 1 supp. in one day. The course is 20 supp.

With urogenital infections (chlamydial and trichomonas urethritis, chlamydial prostatitis): the drug is prescribed 1 supp. 2 times / day for 1 day, then – 1 supp. in one day. The course is 10-15 supp. depending on the severity of the pathological process.

With salpingoophoritis, endometritis in the acute period: 2 suppositories are prescribed for 2 days. 1 time / day, then – 1 supp. with an interval of 72 hours. In the chronic period, the drug is prescribed for 5 days, 1 supp. 1 time / day, then – 1 supp. every 72 hours. The course is 20 soup.

With PID in the acute period: the drug is prescribed in 1 day 2 supp. once, then for 3 days, 1 supp. 1 time / day, then – 1 supp. every other day for 5 days. The course is 10 supp. In the chronic period, the drug is prescribed for 5 days, 1 supp. 1 time / day, then – 1 supp. every 72 hours. The course is 20 supp.

For postoperative rehabilitation of patients with uterine myoma and with complications of the postoperative period in patients of reproductive age: the drug is prescribed for 5 days for 1 supper. 1 time / day, then – 1 supp. in one day. The course is 15 supp.

For the prevention and treatment of surgical complications in the preoperative and postoperative period (including in cancer patients): the drug is prescribed before surgery – within 5 days, 1 supp. 1 time / day, after surgery – 1 supp. every other day (5 supp.) and 5 supp. with an interval of 72 hours. In severe cases of the disease, the initial dose of the drug is 2 supp. once or 1 supp. 2 times / day Course – 20 supp.

In chronic recurrent furunculosis, erysipelas: the drug is prescribed for 5 days for 1 supp. 1 time / day, then – 1 supp. in one day. The course is 20 supp.

For asthenic conditions, neurotic and somatoform disorders, mental, behavioral and post-withdrawal disorders, alcohol and drug addiction: the drug is prescribed for 5 days for 1 supp. 1 time / day, then – 1 supp. after 72 hours. The course is up to 20 supp.

To increase physical performance: the drug is prescribed 1 supp. every other day – 5 supp., then – 1 supp. after 72 hours. The course is up to 20 supp.

For inflammatory diseases of the mucous membrane of the mouth and throat, periodontal diseases: the initial dose of the drug is 1 supp. 1 time / day for 5 days, then – 1 supp. – with an interval of 72 hours. Course – 15 supp.

Overdose

To date, cases of an overdose of Galavit have not been reported.

Special instructions

With the simultaneous use of Galavit with antibiotics, a reduction in the course doses of the latter is possible.

Storage conditions

Keep out of the reach of children, in a dry, dark place at a temperature not exceeding 25 ° C.