Agent for substitution of the synovial fluid RIPART Long is a sterile, pyrogen-free, colorless and transparent viscous solution of high purity sodium hyaluronate produced by biofermentation method. Gualuronat product contains sodium in a concentration of 20 mg / ml Sodium dihydrogen phosphate, Disodium hydrogen phosphate, sodium chloride, water for injection.
Sodium hyaluronate – a sodium salt of hyaluronic acid, glycosaminoglycan formed by the groups represented by D-glucuronic acid and N-acetyl-O-glyukozaminodisaharid. It is widely represented in the extracellular matrix in both animals and humans.
Sodium hyaluronate is a member of a small group of substances which are the same for all living organisms. Sodium hyaluronate is a natural polysaccharide which is included in all body tissues, with particularly high concentrations in the sodium hyaluronate is contained in the synovial fluid and skin.
Agent for substitution of the synovial fluid composed of Long RIPART produced in a biosynthetic pathway stabilized and purified sodium hyaluronate. Sodium hyaluronate in the body is a natural component of synovial fluid, which lubricates the joint cartilage and ligaments, as well as a shock absorber.
It is known that synovial fluid in affected joints, has a lower viscosity and elasticity than healthy synovial fluid in the joints. Introduction of sodium hyaluronate into the joint in order to restore viscosity and elasticity can reduce pain and restore mobility in the joint.
This medical product should only be used by specially trained personnel in the health care environment.
Inhalation Ltd., Russia
The active ingredient is:
gualuronat sodium 20 mg.
The product is intended for administration to replace if damaged synovial fluid of joints, to eliminate pain and improve joint mobility.
Means to replace synovial fluid RIPART Long used in osteoarthritis and other degenerative, traumatic and post-traumatic changes in the joints: the knee, hip and other major joints, as well as an aid in orthopedic surgery.
It prohibited to use in patients suffering from hypersensitivity (allergy) for products containing sodium hyaluronate.
Input means prohibited to replace the synovial fluid in a joint RIPART Long patients observed or infectious skin diseases in the portion at which the injection is supposed to conduct.
Means to replace synovial fluid RIPART Long has good portability.
Possible side effects include extending momentary pain at the injection site and (or) swollen joint.
Typically, such reactions have consequences for 2-3 days and do not affect the effectiveness of the treatment. Cases of allergic and anaphylactic reactions are rare.
Failure to observe the precautions for intraarticular injection, in very rare cases it may be septic arthritis.
How to accept, acceptance rate and dosage
Agent for substitution of the synovial fluid RIPART Long singly administered intra-articularly (at intervals of one week), a total of 5 injections do. Subcutaneous administration of lidocaine or other local anesthetic may be recommended to introduce RIPART Long product.
Input means for the replacement of synovial fluid RIPART Long in the affected joint can only qualified physician or other medical personnel in health facilities, properly equipped to perform intra-articular injections.
Concurrent use is prohibited (for skin preparation) disinfectants comprising quaternary ammonium salts, as sodium hyaluronate in their presence may form a precipitate.
Do not use the tool for replacement of synovial fluid RIPART Long, if the blister pack is opened or shows signs of damage. Do not use the medication after its expiration date printed on the package.
Be sure to strict compliance with all the strict requirements for the introduction of aseptic products.
If necessary (if any), remove the effusion before introduction means for replacing synovial liquid RIPART Long.
It is necessary to remove the screw cap and the syringe tip cap of the needle with all the aseptic rules. Means for the Introduction of substitution of the synovial fluid into the joint RIPART Long should be implemented using an appropriately sized needle (selected taking into account the size of the joint). The needle in the product packaging is not included.
Inject each joint in full volume means for replacing synovial liquid RIPART Long (2 ml into the knee or hip joint, in 1 ml shallow joint). If you have a doctor’s prescription, suggesting the introduction of a few joints, each joint is necessary to use a separate syringe.
Pre-filled syringe is intended for single use only and must be used immediately after removal from the packaging.
Any remaining amount of funds for replacement of synovial fluid RIPART Long must be disposed of, using it is no longer subject.
Means to replace synovial fluid RIPART Long is a disposable medical products (no reuse).
At a temperature not exceeding 25 ° C and less than + 2 ° C.
To prepare skin prohibited simultaneously use disinfectants comprising quaternary ammonium salts, as sodium hyaluronate in their presence may form a precipitate.
Intravascular administration is forbidden because of the possibility of systemic adverse side effects. Do not use the tool for replacement of synovial fluid RIPART Long during intraocular surgery.
– The safety and efficacy of this drug injecting in parallel with other intra-articular injections have not been studied
– The effectiveness of a single cycle of procedures, consisting of less than 5 injections, not installed
– You should always follow all the strict requirements for aseptic injection technique
– In the case of articular effusion, remove it before the introduction of tools to replace synovial Jew
– Tool for replacement of synovial fluid RIPART Long should be used with caution in patients with signs of impaired venous or lymphatic drainage of the lower limbs
– In bilateral treatment should use separate syringes for each knee or hip
– Do not use local anesthetics, if you know that the patient has an allergy or hypersensitivity to local anesthetics
– Do not attempt to inject into the hip joint under fluoroscopic guidance and with the use of radiopaque materials, if you know that the patient has an allergy or sensitivity to x-ray contrast media
Sterile contents. Pre-filled syringe is for single use only. Contents of the syringe should be used immediately after opening the container. Any unused amount of funds for replacement of synovial fluid RIPART Long should be disposed of.
Do not use the tool for replacement of synovial fluid RIPART Long, if the blister package is opened or damaged.