FarmGruppa: A preparation for topical treatment of benign skin lesions with a cauterizing and mummified action
Marden Tsink® Max represents a 50% aqueous solution of zinc chloropropionate and 2-chloropropionic acid. For external and topical application on the affected areas of the skin or mucous membrane the drug is able to interrupt the growth and activity of pathologically modified cells and tissues, including benign tumors of the skin and mucosa, through antiokoagulyatsii, dehydration and devitalization. When applied to the affected areas of the drug leads to fixation, followed by mummification pathologically altered tissue, with which the drug comes into contact.
The direct action of the drug is expressed in the skin and mucosal discoloration with the appearance characteristic of a pale gray color. Subsequently devitalized diseased tissue dries up and changes color to dark brown because of the mummification. Mummified scab separated only after a complete re-epithelialization spontaneously after 2-3 weeks. Wound goes without complications, especially in the absence of secondary infection, leaving no significant scars, deformation adjacent tissue or organ dysfunction.
When applied to the affected skin or mucosa Marden Tsink® Max not absorbed and systemic effects on the organism has not.
PharmVILAR FPK, Russia
ml of 1:
– zinc 2-chloropropionate 1.5% solution in 2-chloropropionic acid.
- vulgar warts;
- flat warts;
- plantar warts;
- anogenital warts;
- akrohordonov (cutaneous horn);
- seborrheic keratitis;
- benign nevi (malopigmentnyh, amelanotic, papillomatoznyh, fibroepithelial, Sutton nevi), tested for purity.
- pronounced tendency to form keloids;
- malignant tumors of the skin and mucous membranes;
- the age of 18 years;
- increased sensitivity to the drug.
Use of a preparation Marden Tsink® Max in rare cases can cause a change in pigmentation of the skin and formation of surface skin scarring.
In normal flow epithelialization process of infection and lack of secondary independent compartment mummified eschar probability of such adverse effects is extremely small.
There may be swelling of the tissue, very rarely, if individual sensitivity to the drug allergic reactions such as pruritus.
How to accept, acceptance rate and dosage
For topical use
The treatment process is conducted in an outpatient setting under the supervision of a physician. The procedure does not require anesthesia. The drug is applied using a plastic spatula, cotton swab or with the glass capillary to the pre degreased surface with 70% alcohol formation. Treatment is carried out for 1-3 applications before the whitish-gray coloring. Changes in tissue color occurs within 2-3 minutes after application of the drug. When the presence of pronounced hyperkeratosis for 5-7 minutes. At the same time there is a change in the consistency of the tumors more dense. Dosage depends on the type, size, density and degree of hyperkeratosis, and may be 0.02 ml-0.2 ml. The maximum daily dose – 0.2 ml.
The number of treatment sessions varies from 1 (flat warts) to 3-4 (plantar warts) until complete disappearance element with an interval between sessions is not less than 24 hours. Around tumors after drug application Marden Tsink® Max observed transient streak hyperemia and edema which disappears after 25-40 min after the completion of the procedure. Any additional remedial measures after the application of the drug is required. The next day, after the application of the pathological focus mummified, becomes dark brown shade and sharply reduced in size. Mummified scab separated only after complete epithelialization spontaneously after 2-3 weeks. Wound goes without complications, especially in the absence of secondary infection, leaving no significant scarring, scarring and deformation adjacent tissue or organ dysfunction.
For topical application,
Treatment of anogenital warts. Treatment is carried out in an outpatient setting under the supervision of a physician, the procedure does not require anesthesia. The drug is applied universal probe or applicator. After application of the drug is changed to the color fabrics whitish-gray coloration. The volume of applied preparation depends on the size and formation of the area affected, and may be from 0.02 ml to 0.2 ml. In no more than 2-3 lesions total area of up to 3 cm2 can be treated during each procedure. The maximum daily dose – 0.2 ml. In the presence of more extensive lesions drug treatment should be carried out in several steps at intervals of not less than 24 hours. When applying the preparation Marden Tsink® Max arises small mucosal edema. Within 2-3 days after use of the drug occurs necrotic tissue rejection. Full recovery occurs within 10-14 days. For large anogenital warts in case of incomplete necrosis may re-applying the product in 5-7 days.
In a dry place, protected from light at a temperature not higher than 25 ° C
Zinc 2-chloropropionate in 1.5% solution of 2-chloropropionic acid
Interaction preparation Marden Tsink® Max with other medications external action is not set.
Before opening the bottle should shake and move the solution caught in the upper part of the bottle at its bottom. After opening, the vial must be in the upright position.
Mardi Tsink® Max contains in its composition acid. Avoid getting the drug on healthy skin or mucosa. If the drug occurred the accidental Marden Tsink® Max on healthy skin or mucosa must both use the water-wet preparation can be removed faster cotton swab.
In the treatment of the affected skin areas near the eye area, special precautions should be taken. Avoid getting product in eyes. If the drug occurred the accidental Marden Tsink® Max in the eye, an urgent need to wash out large amounts of water and 1% sodium hydrogen carbonate solution, and then seek medical attention.
You can not remove the mummified scab scraping or by mechanical means. Scab should be separated from healthy skin or mucous membrane alone, or may be in breach of tissue healing processes and scarring.
Until reaching complete healing of the skin or mucous membrane is not recommended to swim in the pool and open water, and avoid direct exposure to sunlight and ultraviolet radiation. On the day of treatment is recommended to limit water treatments.
It is desirable to complete epithelialization avoid trauma and contamination of the treated pathological focus.
Before you dispose of the vial should be drug residues rinse under running water. Empty bottle can be thrown in the trash.