Marvelon – is a combined oral contraceptive. Each tablet contains a small amount of two different female sex hormones – desogestrel (progestin) and ethinyl estradiol (estrogen).
Because of the small amounts of hormones Marvelon referred to as low-dose oral contraceptives.
Since all of the pills in the pack contain the same amount of the same hormones, Marvelon relates to a monophasic combined oral contraceptives.
The drug also has an additional non-contraceptive pharmacological effect:
- While taking the drug menstruation becomes less abundant and painful;
- In women taking birth control pills less often observed anemia, some diseases of the uterus, ovaries, mammary glands;
- Has a beneficial effect on the skin, especially improving its condition when acne vulgaris.
After cessation of fertility drug is quickly restored.
For women, adults prescribed by a doctor for women of childbearing age
Desogestrel 0.15 mg;
Ethinylestradiol 0.03 mg.
Colloidal silicon dioxide;
Do not take Marvelon, if you have at least one of those diseases or conditions that are specified below. This should be reported to your doctor before making a decision on the admission of the drug Marvelon:
- thrombosis (arterial or venous) currently or history (including deep vein thrombosis, pulmonary embolism, myocardial infarction, stroke);
- Having now or history possible clinical manifestations of thrombosis (including coronary artery disease or angina pectoris);
- Diabetes mellitus with vascular disease;
- the presence of severe or multiple factors, venous or arterial thrombosis (see “Side effect».);
- The presence of current or a history of severe liver disease (when the liver function tests have not returned to normal);
- Having now or a history of liver tumors (benign and malignant);
- or suspected hormone-dependent malignant tumor of the genital organs or the breasts;
- Vaginal bleeding of unknown etiology;
- or suspected pregnancy, lactation;
- hypersensitivity to any component of the drug;
- Migraine with focal neurological symptoms;
If the drug is used in the background of one of the following conditions, you may need regular medical supervision. Before you start taking this medication be sure to tell your doctor about the following conditions / diseases:
- Do you smoke;
- Do you suffer from migraine;
- Do you suffer from epilepsy;
- you have diabetes;
- you are overweight;
- you have high blood pressure;
- you have a disease of the heart valves or heart rhythm disorder;
- you have inflammation of the veins (superficial thrombophlebitis);
- you have varicose veins;
- In the next of kin had thrombosis, myocardial infarction or stroke;
- you or the next of kin or upgraded has been raised cholesterol or triglycerides in the blood;
- who has ever had breast cancer in the immediate family;
- you have a disease of the liver or gall bladder;
- you have Crohn’s disease or ulcerative colitis (chronic inflammatory bowel disease);
- you have systemic lupus erythematosus;
- you have hemolytic uremic syndrome (a bleeding disorder that causes kidney failure);
- you have sickle cell anemia;
- you have or have had chloasma (yellowish-brown patches of skin pigmentation, especially on the face). In this case, should avoid prolonged exposure to sunlight or ultraviolet radiation.
It reported the following adverse reactions in patients taking Marvelon:
Headache, gastralgia, nausea, vomiting;
Tenderness and engorgement;
Increased body weight, glucose intolerance, fluid retention in the body;
changes in libido;
Eyelid edema, skin rash, nodular erythema, conjunctivitis, discomfort when wearing contact lenses;
Thrombophlebitis, thromboembolism (perception disorders can manifest: blurred vision, hearing loss);
Increased blood pressure;
Intermenstrual bleeding, a change in vaginal secretion may develop vaginal candidiasis.
With prolonged use (rarely) – chloasma, hepatocellular adenoma.
They can occur in the first few months of using the drug, and usually diminish over time.
How to accept, acceptance rate and dosage
Inside, in the order directed on the package every day at about the same time, if necessary with a little water.
Take Table 1. a day for 21 days. Pills of the next pack should be started 7 days after the end of the previous one. During these 7 days occurs menstrualnopodobnoe bleeding. It usually starts on day 2-3 after the last tablet and may not end before you start taking the tablets from the next package.
How to start taking Marvelon preparation ® , if not used hormonal contraceptives during the last month
Pills due to start on day 1 of the menstrual cycle. One can start receiving the drug for 2-5 days after the beginning of the menstrual cycle, but in this case it is recommended to use an additional (non-hormonal) contraceptive method for the first 7 days of tablet in the initial cycle.
The transition to other COCs
It is desirable to begin receiving drug Marvelon ® on the day after the last tablet previously used preparations containing hormones, or at least immediately after the tablet-free interval, or after administration of the tablet containing no hormones.
Transition from formulations containing only a progestogen ( “mini-pill”, injections, implants)
Women who take a “mini-pill” can go to the reception of the drug Marvelon ®
on any given day: using an implant – on the day of its removal; using a drug by injection – the day following injection administration. In all cases, during the first 7 days of taking the drug Marvelon ® is recommended to use additional methods of contraception.
After the abortion I trimester
A woman can begin taking the drug immediately. No need to use any additional methods of contraception.
After delivery or abortion in the II trimester
It is recommended to start taking the drug at 21 or 28 days after birth or abortion made in the II trimester of pregnancy. At the beginning of the drug at a later time recommended during the first 7 days of dosing Marvelon ® utilize barrier methods of contraception. In any case, if a woman after childbirth or abortion before you start taking the drug Marvelon ® were sex, pregnancy should be excluded before the start of dosing, or wait until the first menstrual period.
Use of the drug is contraindicated during lactation.
If you skip the next dose
If reception of the next tablet arrested less than 12 hours, contraceptive reliability is not reduced. A woman should take the tablet as soon as she thought about it, and the next tablet at the usual time taken.
If reception of the next tablet delayed more than 12 hours, contraceptive reliability may be reduced. In this case, should be guided by the following rules:
A woman should take the missed pill as soon as she thought about it, even if it means taking 2 tablets. at the same time. Then, should continue to receive the usual way. Additionally, you should use barrier methods of contraception for the next 7 days. If a woman has had sexual intercourse within the preceding 7 days, the possibility of pregnancy should be considered. The more missed tablets and the closer a break from taking the drug at the time of sexual intercourse, the higher the risk of pregnancy.
A woman should take the missed pill as soon as she thought about it, even if it means taking 2 tablets. at the same time. Then, should continue to receive the usual way. Provided that the woman is on the pill in time for the 7 days preceding the first missed dose, there is no need to use extra (non-hormonal) method of contraception. Otherwise, or if the woman missed more than one tab., It is recommended to use additional methods of contraception for the next 7 days.
Contraceptive reliability may be reduced due to the subsequent break in taking the drug. This can be avoided by adapting the dosing scheme. If one uses any of the following two schemes, there is no need for additional measures of contraception, with the proviso that the woman took pills time within 7 days prior to the first missed dose.
Otherwise it is recommended to use one of the two following schemes and additional contraceptive measures during the next 7 days.
A woman should take the missed pill as soon as she thought about it, even if it means taking 2 tablets. at the same time. Then, should continue to receive the usual way. New pack should be started as soon as the current ends, ie should not make the break. The probability of occurrence of withdrawal bleeding until the end of the second pack is low, but some may experience spotting or heavy bleeding even during treatment.
It can be recommended to stop taking the drug from the current package. Women should take a break from taking Marvelon preparation ® for up to 7 days, including the days she forgot to take a pill, and then start a new pack.
At the admission to taking the drug and the subsequent absence of bleeding in the immediate break in the reception should take into account the possibility of pregnancy.
The recommendations in the event of vomiting
If vomiting occurs within 3-4 hours following ingestion, absorption may be incomplete. In this case, use recommendations for skipping the next dose. If a woman does not want to change their usual dosage regimen, it is necessary to take additional (s) tablet (s) from a new package.
How to change the term onset of menstruation
To delay menstruation, should continue receiving the tablets of other packaging product Marvelon ®
without the usual break in reception. To delay menstruation can be for any period up to the end of the tablets in the second pack. During this period, the woman may experience spotting or heavy bleeding. Acceptance of the drug in the usual way should be resumed after the 7-day interval in taking.
In order to shift the flow of blood on the day of the week other than the one that is expected, subject to the usual regimen can reduce the normal break in reception for as many days as necessary. The shorter the interval, the higher the risk of lack of menstruation during the break and the occurrence of abundant or spotting while taking the second pack of the drug.
The drug should be protected from light and moisture at a temperature of from 2 ° to 30 ° C.
Interactions with certain drugs can lead to excessive bleeding and inefficiency of oral contraceptives. Such cases were observed in the reception of hydantoins, barbiturates, primidone, carbamazepine, rifampicin, isoniazid; they are possible in the appointment oxcarbamazapine, topiramate, felbamate and griseofulvin.
Reduced efficacy of oral contraceptives was also observed when taking certain antibiotics such as ampicillin, tetracycline, neomycin, penicillin, chloramphenicol, and activated charcoal, laxatives.
Marvelon reduces the effectiveness of oral anticoagulants, anxiolytics (diazepam), the tricyclic antidepressants, theophylline, caffeine, hypoglycemic drugs, clofibrate, corticosteroids.
Always tell the doctor, who appoints you to the pill, which medicines you are already using. If the doctor prescribes you other medicines, tell him that you are taking Marvelon.
In the application shown Marvelona systematic medical examination.
With care prescribe a drug at high risk of thrombosis, heart failure symptoms, lesions of heart valves, atrial arrhythmia, hypertension, epilepsy, migraine, Crohn’s disease, sickle-cell anemia.
Smoking women older than 35 years should quit smoking if they intend to use Marvelon for contraception.
Estrogenosoderzhaschie drugs may temporarily increase the risk of thrombosis in patients undergoing surgery and prolonged immobilization.
In women with tumor formation in the abdomen and / or sharp pains in the abdomen, it should be excluded the presence of hepatocellular adenomas.
Women who have been chloasma (using estrogeno- and / or progesteronosoderzhaschih drugs) should avoid exposure to the sun.
Marvelon efficiency may decrease in case of missing its reception, as well as diarrhea and / or vomiting arising in the first 4 hours after ingestion.
Serious consequences receiving Marvelon large number of tablets are not reported.
If you have taken several tablets, you may experience nausea, vomiting, vaginal bleeding.
If you discover that a child swallows the pill, contact your doctor.