Nobazit capsules 250 mg, 20 pcs.

active substance:

N-methyl-4-benzylcarbamidopyridinium iodide (enisamia iodide) (in terms of 100% anhydrous substance) – 250 mg.

excipients (core):

lactose monohydrate (milk sugar) – 66.8 mg,

microcrystalline cellulose (vivapur 101) – 20.0 mg,

sucrose (refined sugar) – 18.0 mg,

povidone (low molecular weight medical polyvinylpyrrolidone or Plasdon K -17) – 7.2 mg,

copovidone (plasdone S-630) – 2.8 mg,

crospovidone (polyplasdone XL-10) – 7.6 mg,

talc – 3.8 mg,

calcium stearate – 3.8 mg.

excipients (shell): Aquarius Prime BAN314047 Yellow – 12 mg (hypromellose – 7.92 mg, titanium dioxide – 2.6874 mg, capryl / caprylate (caprylic / capric triglyceride) – 1.08 mg, iron dye yellow oxide – 0.084 mg, iron dye red oxide – 0.0006 mg, quinoline yellow dye – 0.228 mg).

ATC code: J05 AX

Pharmacological properties

Pharmacodynamics
Nobazit® is an antiviral agent derived from isonicotinic acid. Effectively suppresses the action of influenza viruses and other causative agents of acute respiratory viral infections (ARVI) due to the direct (inhibitory) effect on the process of penetration of viruses through the cell membrane.
It has interferonogenic properties, increases the concentration of endogenous interferon (interferon alpha and interferon gamma) in blood plasma by 3-4 times. Increases the body’s resistance to viral infections.
Reduces acute clinical manifestations of viral intoxication, helps to reduce the duration of the disease.

Pharmacokinetics

After oral administration, enisamia iodide quickly enters the bloodstream, its maximum concentration in the blood is observed 2-2.5 hours after consumption. Enisamia iodide and its metabolites circulate for a long time in the bloodstream (half-life is 13.5-14 hours), are metabolized in the liver and are rapidly excreted from tissues (half-life is 2-3 hours). It is excreted 90-95% in the urine in the form of metabolites.

Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

Sucrase / isomaltase deficiency, fructose intolerance.

Children under 18 years of age, pregnancy, lactation.

The presence of allergic reactions, regardless of the nature of the allergen in the history.

Severe organic damage to the liver and kidneys.

Nobazit® enhances the effect of antibacterial and immunomodulating agents.

A combination of this drug with ascorbic acid and other vitamins is advisable. Also, Nobazit® can be administered simultaneously with the use of recombinant interferon.

If you are using the above or other drugs (including over-the-counter), consult your doctor before using Nobazit®.