Irbitskiy KhFZ, Russia
N-methyl-4-benzylcarbamidopyridinium iodide (enisamia iodide) (in terms of 100% anhydrous substance) – 250 mg.
lactose monohydrate (milk sugar) – 66.8 mg,
microcrystalline cellulose (vivapur 101) – 20.0 mg,
sucrose (refined sugar) – 18.0 mg,
povidone (low molecular weight medical polyvinylpyrrolidone or Plasdon K -17) – 7.2 mg,
copovidone (plasdone S-630) – 2.8 mg,
crospovidone (polyplasdone XL-10) – 7.6 mg,
talc – 3.8 mg,
calcium stearate – 3.8 mg.
excipients (shell): Aquarius Prime BAN314047 Yellow – 12 mg (hypromellose – 7.92 mg, titanium dioxide – 2.6874 mg, capryl / caprylate (caprylic / capric triglyceride) – 1.08 mg, iron dye yellow oxide – 0.084 mg, iron dye red oxide – 0.0006 mg, quinoline yellow dye – 0.228 mg).
ATC code: J05 AX
Nobazit® is an antiviral agent derived from isonicotinic acid. Effectively suppresses the action of influenza viruses and other causative agents of acute respiratory viral infections (ARVI) due to the direct (inhibitory) effect on the process of penetration of viruses through the cell membrane.
It has interferonogenic properties, increases the concentration of endogenous interferon (interferon alpha and interferon gamma) in blood plasma by 3-4 times. Increases the body’s resistance to viral infections.
Reduces acute clinical manifestations of viral intoxication, helps to reduce the duration of the disease.
After oral administration, enisamia iodide quickly enters the bloodstream, its maximum concentration in the blood is observed 2-2.5 hours after consumption. Enisamia iodide and its metabolites circulate for a long time in the bloodstream (half-life is 13.5-14 hours), are metabolized in the liver and are rapidly excreted from tissues (half-life is 2-3 hours). It is excreted 90-95% in the urine in the form of metabolites.
Application during pregnancy and lactation
Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.
Sucrase / isomaltase deficiency, fructose intolerance.
Children under 18 years of age, pregnancy, lactation.
The presence of allergic reactions, regardless of the nature of the allergen in the history.
Severe organic damage to the liver and kidneys.
Allergic reactions: hypersensitivity reactions, including skin rashes, urticaria, angioedema, itching.
On the part of the digestive system: dry and bitter taste in the mouth, swelling of the oral mucosa, hypersalivation, yellowing of the tongue, nausea, vomiting, heartburn, abdominal pain, heaviness in the right hypochondrium, diarrhea, abdominal distension.
From the respiratory system: shortness of breath, throat irritation.
In the post-registration period, in isolated cases, the following adverse reactions were noted: headache, dizziness, weakness, fluctuations in blood pressure.
If you have any side effects indicated in the instructions or they are aggravated, or you notice any other side effects not listed in the instructions, inform your doctor
Nobazit® enhances the effect of antibacterial and immunomodulating agents.
A combination of this drug with ascorbic acid and other vitamins is advisable. Also, Nobazit® can be administered simultaneously with the use of recombinant interferon.
If you are using the above or other drugs (including over-the-counter), consult your doctor before using Nobazit®.
How to take, course of administration and dosage
Begin treatment when the first signs of the disease appear. If after 3 days of treatment there is no improvement or symptoms worsen or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the method of administration and the doses indicated in the instructions.
Nobazit® is taken orally after meals, without chewing, 0.5 g 3 times a day.
The maximum single dose is 1 g, the daily dose is 2 g.
The recommended course of treatment is 5 to 7 days.
Taking Nobazit® does not affect the ability to drive vehicles and various mechanical equipment.
Keep out of the reach of children.