Ostenil – reducing viscoelastic properties of the synovial fluid
The synovial fluid (SJ) performs an essential role in the homeostasis of the joints. In addition to the power of cartilage (the latter does not contain blood vessels) SJ protects it mechanically due to their unique viscoelastic properties. These characteristics SJ attached stromal its main component – hyaluronic acid
The important part of the pathogenesis of osteoarthritis is to reduce the volume and viscosity of the Union of Journalists, which leads to increased mechanical load on the articular cartilage, and their gradual destruction, hence the emergence of pain and limitation of joint mobility. To restore synovial balance shown intraarticular injection of exogenous hyaluronic acid.
Highly purified hyaluronic acid produced by bacterial fermentation, is hypoallergenic substance. Rationally selected molecular weight contributes both to restore viscoelasticity of the synovial fluid as well as the elaboration of endogenous hyaluronic acid. Mannitol – an antioxidant that promotes the preservation of the therapeutic effect after a single injection of medical products Ostenil® Plus for six months or more
The active ingredients: sodium hyaluronate; mannitol; Water for Injection;
Excipients: sodium chloride; sodium hydrogen phosphate; sodium dihydrogen
Degenerative-dystrophic and traumatic changes in the hip, knee and other synovial joints, with pain and limited mobility.
Hypersensitivity to one of the ingredients.
After intraarticular injection products can be observed the local secondary phenomena such as pain, feeling of heat, redness and swelling. Imposition of ice on the punctured joint for 5-10 minutes, allows to stop such events.
How to accept, acceptance rate and dosage
intra-articularly. Is allowed to use only a doctor.
is introduced into the cavity of the affected joint once. By indications treatment may be supplemented by 1-2 injections with an interval of 14 days. At the same time, you can perform the injections and other joints.
If you have a joint effusion should first make its evacuation, to ensure peace and joint use cold therapy or intra-articular corticosteroid drug. medical devices Ostenil treatment can begin 2-3 days after these procedures.
The contents and outer surface of the syringe filled with medical supplies Ostenil sterile until the broken package integrity and capping the syringe system. The closure system consists of a protective cap, and luer lock cap to prevent unauthorized opening.
Before the injection, you must:
- Remove the filled syringe with medical devices Ostenil® Plus from its sterile packaging.
- to bend the cover to protect against unauthorized opening of the syringe in one and the other side so that the fixing her broken bridge.
- Carefully lift up the lid with a protective cap.
- Connect the desired size (18-25 G) sterile needle and fix it by turning slightly.
- Before injection of the syringe to release air bubbles, if any.
At a temperature of 2-25 ° C (not frozen)
The drug appears to be damaged sterile packaging or syringe, as well as beyond the expiration date (listed on the box) is not subject to use.
Pregnancy and lactation
It is not recommended to use in children, pregnant and lactating women.