Progesterone solution olive oil 2.5% 1 ml of 10 pcs
€30.67 €18.40
Progesterone – progestogen. The hormone of the corpus luteum. It causes a transition of the uterine mucosal proliferation phase induced follicular hormone in the secretory phase, and after fertilization contributes to its transition into a state required for the development of the fertilized ovum.
Decreases Uterine contractility and excitability of muscle and fallopian tubes, stimulates the development of breast end elements. It has no androgenic activity.
Progesterone has little effect on protein metabolism Escrow promotes fat accumulation and glucose in liver and also reduces reabsorption of sodium in the renal tubule.
Progesterone has a blocking action on the secretion of hypothalamic releasing factors LH and FSH, inhibits the formation of the pituitary gonadotropins and inhibits ovulation.
pharmacokinetics
After i / m injection is absorbed rapidly and almost completely. It is metabolized in the liver, most metabolites form conjugates with glucuronic acid and sulfuric acid.
T1 / 2 from the plasma of a few minutes. Excreted in the urine – 50-60% and faeces – more than 10%. The number of metabolites that are excreted with urine varies depending on the luteal phase.
Active substance:
Progesterone
Manufacturer
Dalkhimpharm, Russia
Composition
The active ingredient is:
progesterone
Indications
Dysfunctional uterine bleeding, metrorrhagia, amenorrhea, recurrent miscarriage. Contraception.
Contraindications
Severe liver or kidney disease, hepatitis, thromboembolic disorders, vaginal bleeding not installed genesis, breast carcinoma (except in cases in which the progesterone is used in a combination therapy of the disease).
Side effects
Cardio-vascular system: increased blood pressure.
From a metabolism: edema.
From the digestive system: abnormal liver function, jaundice; rarely (with prolonged use) – nausea, vomiting.
Endocrine system: rare (with prolonged use) – decreased libido, increased body weight, tension and pain in the breast, irregular uterine bleeding.
CNS: rarely (with prolonged use) – headache, depression.
How to accept, acceptance rate and dosage
Individual dosing regimen.
The dose, frequency and duration of treatment are determined by the scheme, depending on the indication and the clinical situation.
Storage conditions
In the dark place, in a tightly closed container at a temperature not higher than 30 ° C
Active substance
Progesterone
Interaction
Reduces the intensity of the action of drugs that stimulate smooth muscle of the uterus, anabolic steroids, gonadotropins of the anterior pituitary.
Reduces the lactogenic effect of oxytocin.
It enhances the action of diuretics, antihypertensive drugs, immunosuppressants.
While the use of barbiturates marked decrease actions of progesterone.
Weight | 0.038 kg |
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Expiration date | 5 years |
Dosage form | injection |