Chrome Pharma, Germany
Sinokrom® is a sterile 1% aqueous solution of sodium hyaluronate with a molecular mass of ~ 1.6 Mill. Daltons in syringes of 2 ml ready to use.
1 syringe (2 mL) Sinokrom® comprises as main substance 20 mg sodium hyaluronate with a molecular mass of ~ 1.6 million daltons, adjuvants:. Sodium chloride, sodium monohydrogenphosphate, citric acid, water for injection.
Pain and limitation of motion as a result of degenerative or traumatic joint changes, synovial fluid containing.
Sinokrom® can not be used in patients with a hypersensitivity to one of the components of the preparation.
Due intraarticular injection to patients with bacterial arthritis should refrain from treatment with this drug to avoid potential complications. The attending physician should be aware of all the immunological and other potential consequences of the use of biological products.
Patients applying Sinokrom®, in very rare cases may be a manifestation of local symptoms (pain, burning sensation, redness and swelling, increase in the content of fluid in the joint cavity).
To avoid these manifestations or when their appearance is recommended to unload the affected joint and within 5-10 minutes of applying to the joint ice pack. When expressed manifestations accompanied by severe pain, the solution should be removed from the affected joint.
It is noted isolated cases allergic reactions (pruritus, rash, urticaria) and anaphylactic reactions.
Sinokrom® stored at temperatures no higher than 25 ° C. Do not freeze!
Currently there is no information on incompatibilities Sinokrom® with other solutions for intra-articular administration.
Do not apply disinfectants comprising quaternary ammonium salts, as hyaluronic acid is deposited in the presence of these substances.
Recommendations for use
Injections of the drug are made by specialist doctors under aseptic conditions. Ready syringe is removed from a sterile case, a rubber cap is removed from luer adapter system small rotation, after which the corresponding worn sterile needle, which is also fixed a small rotation (needle part for injecting supplied). Place administration processed disinfectant containing alcohol. The drug is injected Sinokrom® accurately into the joint cavity by standard procedures, taking into account the anatomical features. The introduction of the drug into the joint cavity should be discontinued if any pain during injection.
Unused until the end of the drug can not be stored. The course of treatment is 3-5 Sinokrom® injections with an interval of one week between the injections. The simultaneous treatment of multiple joints. The treatment of 5 injections may be effective for more than 6 months (depending on the severity of the disease). Allowed repeated courses of treatment.