A bacteriostatic antibiotic from the tetracycline group. It disrupts the formation of a complex between transport RNA and the ribosome, which leads to the suppression of protein synthesis.
Active against gram-positive microorganisms: Staphylococcus spp. (including Staphylococcus aureus, including penicillinase producing strains), Streptococcus spp. (including Streptococcus pneumoniae), Listeria spp., Bacillus anthracis, Clostridium spp., Actinomyces israelii;
gram-negative microorganisms: Haemophilus influenzae, Haemophilus ducreyi, Bordetella pertussis, most enterobacteria (Escherichia coli, Enterobacter spp., including Enterobacter aerogenes, Klebsiella spp., Salmonella spp., Shigella bibliella pibis Rickettsia spp., Borrelia burgdorferi, Brucella spp. (In combination with streptomycin);
with contraindications to the appointment of penicillins – Clostridium spp., Neisseria gonorrhoeae, Actinomyces spp .; active against pathogens Chlamydia trachomatis, Treponema spp.
Microorganisms are resistant to tetracycline: Pseudomonas aeruginosa, Proteus spp., Serratia spp., Most strains of Bacteroides spp. and fungi, viruses, beta-hemolytic group A streptococci (including 44% of Streptococcus pyogenes strains and 74% of Streptococcus faecalis strains).