Venarel Prenatal 1 30 capsules 514 mg

recommended as a dietary supplement - a source of vitamins (A, B1, B2, B3, B5, B6, B7, B12, C, D3, E, folic acid) and minerals (iron, zinc, iodine, selenium) for women planning pregnancy and women during pregnancy (1st trimester).

For women planning pregnancy and women during pregnancy (throughout the 1st trimester), take 1 capsule once a day with food, drinking a sufficient amount of water. It is recommended to consult a doctor before use. Individuals with thyroid gland disorders are advised to consult an endocrinologist.

Iron (II) bisglycinate, Vitamin C (L-ascorbic acid), gelatin (capsule shell), Vitamin E (DL-alpha tocopherol acetate), potassium iodide, Vitamin B3 (niacin, nicotinamide), zinc oxide, sodium selenate, magnesium salt of fatty acids (anti-caking agent), Vitamin D3 (cholecalciferol), Vitamin B5 (calcium D-pantothenate), Vitamin A (retinyl acetate), Vitamin B12 (cyanocobalamin), Vitamin B6 (pyridoxine hydrochloride), Vitamin B1 (thiamine hydrochloride, thiamin), Vitamin B2 (riboflavin), folic acid (L-methylfolate calcium), Vitamin B7 (biotin).
Non-GMO.

individual intolerance to the components of the product; conditions in which iodine-containing medications are contraindicated.

Dietary supplement (BAA)
Not a medicinal product.
Consult a doctor before use.

“Venarel Prenatal 1” is a biologically active food supplement for use during the planning stage and throughout the first trimester of pregnancy as an additional source of vitamins and trace elements, contributing to the normal growth and development of the fetus.

“Venarel Prenatal 1”
Is not a medicinal product
The packaging of “Venarel Prenatal 1” is designed for 30 days (30 capsules).

All components of “Venarel Prenatal 1” are selected considering:

• the latest recommendations for managing pregnancy approved by the Ministry of Health of the Russian Federation;
• the recommendations of the WHO* on alimentary anemia;
• the norms of physiological needs for energy and nutrients for women preparing for pregnancy and during the first trimester of pregnancy, approved in the methodological recommendations by the Chief State Sanitary Doctor of the Russian Federation[1].

FOLIC ACID (Vitamin B9) [1, 4, 5, 6, 7, 8, 9, 10, 26, 27]
The Russian Society of Obstetricians and Gynecologists recommends taking folic acid at a dose of 400-800 mcg per day for 2-3 months before conception and during the first 12 weeks of pregnancy to reduce the risk of neural tube defects in the fetus. The intake of folic acid reduces the risks of:

• miscarriage,

• partial or complete placental abruption,

• development of folate-deficiency anemia in the mother.

Folate intake during pregnancy helps prevent:
• the development of congenital neural tube defects in the fetus;
• anomalies in the development of the brain, cardiovascular system, limbs, and major arteries;
• cleft lip (“harelip”), umbilical hernia, Down syndrome.

Folic acid in the form of L-methylfolate, unlike synthetic folic acid, does not require additional activation by enzymes and is absorbed even with gastrointestinal disorders.

IODINE [1, 28]

• is involved in the functioning of the thyroid gland,

• contributes to the healthy development of the brain and nervous system of the child.
The Russian Society of Obstetricians and Gynecologists recommends taking iodine at a dose of 200 mcg per day for 2-3 months before conception and throughout pregnancy to eliminate iodine deficiency and prevent developmental disorders of the fetal nervous system.

VITAMIN D3 (cholecalciferol) [4, 24, 28]

• contributes to the normal development of bones and teeth in the child,

• helps maintain the health of the mother,

• affects the development of the child's brain,

• regulates immunity and placental function.
The Russian Society of Obstetricians and Gynecologists recommends that pregnant women at risk of vitamin D deficiency take cholecalciferol throughout pregnancy at a dose of 500-1000 IU (12.5-25 mcg) to prevent vitamin D deficiency and reduce the risk of obstetric complications.

SELENIUM [1, 16]

• is necessary for the normal functioning of the thyroid gland, which is important for regulating metabolism and hormone production in both the mother and the fetus.

IRON [1, 4, 27]

• is involved in the formation of hemoglobin, which ensures the transport of oxygen to tissues;

• helps reduce fatigue and tiredness in the mother.
The World Health Organization recommends a daily intake of 30 mg of elemental iron for the prevention of anemia in pregnant women in regions where the prevalence of anemia among pregnant women is 20-40%.

VITAMIN C (ASCORBIC ACID) [22, 23]

• helps with the absorption of iron,

• supports the immune system.
Vitamin C consumption helps reduce the risk of gestational diabetes in pregnant women.
Regular intake of vitamin C reduces the frequency of urinary infections in pregnant women by half.

VITAMIN A (RETINOL) [1, 4, 31]
Contributes to:

• the proper formation of the placenta,

• the normal functioning of the mother's liver and immune system,

• participates in the processes of growth and development of bone tissues, maintaining immunity and vision.

VITAMIN E (?-TOCOPHEROL) [1, 4]
• is an antioxidant and a universal stabilizer of cell membranes;
• is necessary for the functioning of the gonads and heart muscle;
• reduces the risks of venous thromboembolism.

ZINC [1, 4]
• plays an important role in the processes of synthesis and breakdown of carbohydrates, proteins, fats, and nucleic acids;
• affects the activity of hormones and vitamins;
• participates in the process of proper tissue formation.

B VITAMINS
Vitamin B1 (thiamine) [1]
Ensures the normal functioning of the nervous system, important for converting carbohydrates into energy.
Vitamin B2 (riboflavin) [4]
Participates in energy metabolism to maintain the health of the skin, eyes, and nervous system during pregnancy.
In case of vitamin B2 deficiency in pregnant women, symptoms include peeling skin around the mouth, on the wings of the nose, ears, changes in tongue color to purple, photophobia, and vision disturbances in the dark.
Vitamin B3 (PP, niacinamide, niacin) [4]

• is involved in regulating cellular respiration, energy release from fats and carbohydrates,

• affects hematopoiesis, regulates blood clotting,

• improves oxygen supply to the heart and enhances its contractile ability.
Vitamin B3 deficiency in pregnant women manifests as fatigue, dizziness, sleep disturbances, palpitations, pallor, and dry skin.

Vitamin B5 (pantothenic acid) [1, 29, 30]

• supports adrenal cortex function,

• helps the normal functioning of nerve cells,

• contributes to the elimination of toxins from the body.

Vitamin B6 (pyridoxine) [1, 4]

• reduces nausea and vomiting in pregnancy toxemia,

• improves magnesium absorption in the intestines,

• contributes to the normal development of the fetus.

Vitamin B7 (Biotin, Vitamin H) [1]

• supports the health of the mother's skin, hair, and nails.

Vitamin B12 (cyanocobalamin) [20, 21]

• plays an important role in DNA synthesis,

• is involved in the processes of forming the nervous system, hematopoiesis, and fetal development.
Vitamin B12 deficiency in pregnant women is associated with preeclampsia and premature birth.

Nutritional value of 1 capsule: proteins - 0.10 g, fats - 0.03 g, carbohydrates - 0.23 g. Energy value of 1 capsule - 7.088 kJ / 1.69 kcal.

Content of biologically active substances in 1 capsule (daily dosage):

Amount in 1 capsule % of the daily requirement for active substances for women during pregnancy (1st trimester)(1)

Vitamin A 800 mcg 100 100
Vitamin B1 (thiamine hydrochloride) 1.5 mg 100
Vitamin B2 (riboflavin) 1.8 mg 100
Vitamin B3 (niacin) 20 mg 100 100
Vitamin B5 (pantothenic acid) 6 mg 120(2)
Vitamin B6 (pyridoxine hydrochloride) 2 mg 100
Vitamin B7 (biotin) 50 mcg 100
Vitamin B12 (cyanocobalamin) 4.5 mcg 150(2)
Folate (L-methylfolate calcium) 600 mcg 150(2)
Vitamin C (L-ascorbic acid) 110 mg 100
Vitamin D3 (cholecalciferol) 15 mcg 100
Vitamin E (DL-alpha tocopherol acetate) 15 mg 100
Iron (II) 30 mg 167(2)
Zinc 12 mg 100
Iodine 200 mcg 134(2)
Selenium 55 mcg 100

(1) - according to MR 2.3.1.0253-21 “Norms of physiological needs for energy and nutrients for various population groups of the Russian Federation.”
(2) - does not exceed the upper permissible level of consumption, according to “Unified sanitary-epidemiological and hygienic requirements for products (goods) subject to sanitary-epidemiological supervision (control),” Appendix 5.

References:

• MR 2.3.1.0253-21. 2.3.1. Hygiene of nutrition. Rational nutrition. Norms of physiological needs for energy and nutrients for various population groups of the Russian Federation. Methodological recommendations (approved by the Chief State Sanitary Doctor of the Russian Federation on 22.07.2021)

• UNIFIED SANITARY-EPIDEMIOLOGICAL AND HYGIENIC REQUIREMENTS FOR PRODUCTS (GOODS) SUBJECT TO SANITARY-EPIDEMIOLOGICAL SUPERVISION (CONTROL), Approved by the Decision of the Customs Union Commission on May 28, 2010, No. 299

• Clinical recommendations of the Ministry of Health of the Russian Federation “Normal Pregnancy,” 2023, Russian Society of Obstetricians and Gynecologists

• Micronutrients and reproductive health: a guide / O. A. Gromova, I. Yu. Torshin. - 2nd ed., revised and expanded. - Moscow: GEOTAR-Media, 2022. - 832 p.: ill. - DOI: 10.33029/9704-6786-2-MIC-2022-1-832. - ISBN 978-5-9704-6786-2.

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• Assessment of iodine deficiency disorders and monitoring their elimination: a guide for programme managers / WHO, United Nations Children's Fund, International Council for the Control of Iodine Deficiency Disorders. - 3rd ed. - Geneva, 2007. - P. 1-97.

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• World Health Organization. (?2017)?. Nutritional anaemias: tools for effective prevention and control. World Health Organization. https://apps.who.int/iris/handle/10665/259425. License: CC BY-NC-SA 3.0 IGO

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