Normomed 50 mg/ml syrup 240 ml bottle

The drug is indicated for adults and children over 3 years old (body weight over 15-20 kg).
• Treatment of influenza and other acute respiratory viral infections (ARVI) as part of combination therapy;
• Treatment of labial herpes (Herpes simplex) as part of combination therapy.

For oral use, after meals, with a small amount of water, at regular intervals (every 8 or 6 hours) 3-4 times a day.
Adults and children over 12 years: 20 ml of syrup 3-4 times a day. Maximum daily dose is 80 ml.
Children aged 3 to 12 years (body weight over 15-20 kg): 50 mg per 1 kg of body weight per day, divided into 3-4 doses.
For children over 3 years, the medication is prescribed according to the table:
Body weight Single dose for 3 times a day Maximum daily dose
15-20 kg 5-6.5 ml 15-20 ml/day
21-30 kg 7-10 ml 21-30 ml/day
31-40 kg 10-13 ml 31-40 ml/day
41-50 kg 13.5-16.5 ml 41-50 ml/day
In case of influenza and other acute respiratory viral infections (ARVI), treatment lasts from 5 to 14 days. After the symptoms disappear, treatment should continue for 1-2 days.
In case of labial herpes, treatment lasts from 5 to 10 days until the symptoms of infection disappear.
Special patient groups
Elderly patients (over 65 years). No dose adjustment is necessary; the medication is used in the same way as for middle-aged patients.
The duration of treatment without consulting a doctor should not exceed 5 days. The decision to continue therapy with the medication for more than 5 days is made by the attending physician based on the clinical picture of the disease.
Use the medication only according to the indications, method of use, and doses specified in the instructions.

100 ml of syrup contains:
active ingredient:
Inosine pranobex 5.00 g
excipients:
Sucrose 65.00 g
Glycerol 5.00 g
Methylparaben 0.18 g
Propylparaben 0.02 g
Citrus flavoring 0.50 g
Purified water up to 100 ml

Clear, slightly yellowish liquid with a characteristic odor.

• Hypersensitivity to inosine pranobex and other components of the product;
• Gout;
• Urolithiasis;
• Chronic renal failure;
• Arrhythmias;
• Hyperuricemia;
• Sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption;
• Pregnancy;
• Breastfeeding period;
• Pediatric age under 3 years (body weight over 15-20 kg);

With caution
Caution should be exercised when co-administering with xanthine oxidase inhibitors, diuretics, zidovudine, in cases of acute renal or hepatic failure, in diabetes mellitus, and with prolonged use of Normomed®. If you are taking any of the listed medications or suffer from the aforementioned conditions, you should consult a doctor before using Normomed®.

Normomed®, like other antiviral agents, is most effective for acute viral infections when treatment is started early in the course of the illness (preferably within the first day). Since inosine is excreted from the body in the form of uric acid, when prescribing the drug alongside medications that increase uric acid concentration or medications that impair kidney function, it is necessary to monitor the concentration of uric acid in the serum.
In elderly patients, an increase in uric acid concentration in the serum and urine occurs more frequently than in middle-aged patients.
Patients with significantly elevated uric acid levels in the body may concurrently take medications that lower its concentration.
Normomed® should be used with caution in patients with acute liver failure, as the drug is metabolized in the liver.
Caution is advised when prescribing concurrently with xanthine oxidase inhibitors, diuretics, zidovudine, in diabetes mellitus, and with prolonged use of Normomed®.
The product contains methylparaben and propylparaben, which may cause allergic reactions (possibly delayed).
Normomed® contains 650 mg of sucrose per 1 ml of syrup, which should be taken into account by patients with diabetes mellitus.
Keep the instruction. It may be needed again. If you have any questions, consult your doctor.

The frequency of adverse reactions is determined according to the following criteria: very common (≥1/10), common (from ≥1/100 to

In case of overdose, gastric lavage and symptomatic therapy are indicated.

Immunosuppressants weaken the immunostimulatory effect of the drug.
The drug should be used with caution in patients taking xanthine oxidase inhibitors (allopurinol) or loop diuretics (furosemide, torasemide, ethacrynic acid) simultaneously, as this may lead to an increase in serum uric acid concentration.
Concurrent use of the drug with zidovudine results in increased plasma concentrations of zidovudine and prolongs its half-life (T1/2). Therefore, when using the drug in conjunction with zidovudine, dose adjustment of zidovudine may be necessary.
If you are taking the above-mentioned medications or other medications (including over-the-counter) before using Normomed®, consult your doctor.

Inosine pranobex is a synthetic purine derivative, consisting of a complex that contains inosine and N,N-dimethylamino-2-propanol in a molar ratio of 1:3.
It possesses immunostimulatory activity and nonspecific antiviral action. The effectiveness of the complex is determined by the presence of inosine, while the second component enhances its availability for lymphocytes.
It restores lymphocyte functions under conditions of immunodepression, increases blastogenesis in the monocyte population, stimulates the expression of membrane receptors on the surface of T-helper cells, prevents the decrease in lymphocyte activity influenced by glucocorticosteroids, and normalizes thymidine incorporation. Inosine pranobex stimulates the activity of T-lymphocytes and natural killers, the functions of T-suppressors and T-helper cells, increases the production of immunoglobulin G (Ig G), interferon-gamma, interleukins IL-1 and IL-2, reduces the formation of anti-inflammatory cytokines - IL-4 and IL-10, and potentiates the chemotaxis of neutrophils, monocytes, and macrophages.
The drug exhibits antiviral activity in vivo against herpes simplex virus, cytomegalovirus, measles virus, human T-cell lymphoma virus (type III), polioviruses, influenza viruses A and B, echovirus (enteropathogenic human virus), encephalomyocarditis viruses, and equine encephalitis virus. The mechanism of the antiviral action of inosine pranobex is associated with the inhibition of viral RNA and dihydropteroate synthase, which is involved in the replication of certain viruses, enhances the suppressed viral synthesis of mRNA in lymphocytes, which is accompanied by a decrease in the synthesis of viral RNA and translation of viral proteins, and increases the production of lymphocytes with antiviral properties of alpha and gamma interferons.
When administered in combination, it enhances the action of interferon-alpha, acyclovir, and zidovudine.

After oral administration, the drug is well absorbed from the gastrointestinal tract. The maximum concentration of ingredients in the blood plasma is reached within 1-2 hours. It is rapidly metabolized and excreted through the kidneys. It is metabolized similarly to endogenous purine nucleotides, resulting in the formation of uric acid. N,N-dimethylamino-2-propanol is metabolized to N-oxide, while 4-acetamidobenzoate is metabolized to o-acylglucuronide. No accumulation of the drug in the body has been detected. The half-life (T1/2) is 3.5 hours for N,N-dimethylamino-2-propanol and 50 minutes for 4-acetamidobenzoate. The drug and its metabolites are excreted from the body by the kidneys within 24-48 hours.

Normomed 50 mg/ml syrup is a medicinal product. It has immunostimulating activity and non-specific antiviral action. It reduces clinical manifestations of viral diseases, accelerates recovery, and increases the body's resistance. Treatment of influenza and other acute respiratory viral infections (ARVI) as part of combination therapy.
Treatment of labial herpes (Herpes simplex) as part of combination therapy. Administered orally, after meals, with a small amount of water, at regular intervals (every 8 or 6 hours) 3-1 times a day.
The dosage regimen is established individually, depending on age, body weight, and the severity of the disease. It is recommended to consult a doctor before use.